Fido and Spot might not have to cower under the bed this summer when fireworks and thunderstorms hit. The first prescription veterinary medicine for treating anxiety over loud noises will soon hit the market.
Veterinary medicine maker Zoetis Inc. said Monday that recently approved Sileo will be available through veterinarians within a week.
Dr. Chris Pachel, a veterinary behaviorist at the Animal Behavior Clinic in Portland, welcomes a medicine tested specifically on dogs that works rapidly but wears off within hours.
“There’s always a need for new options,” said Pachel, who has reviewed some testing data on Sileo but isn’t affiliated with Zoetis.
Fear of loud noises is a common problem for the 70 million dogs in the U.S. Dogs are sometimes so frightened that they jump through windows, destroy doors while trying to escape a room or run into traffic and get hit by cars.
“I have seen the absolutely worst things that can happen with noise anxiety,” Dr. J. Michael McFarland, head of U.S. pet marketing at Zoetis, who previously worked at multiple animal hospitals.
Current treatments range from human anti-anxiety pills such as Xanax and tranquilizers that sedate dogs for many hours but don’t necessarily calm them, to behavioral treatments. Those include confining the dog to a small room or a portable kennel, or trying to desensitize dogs by repeatedly exposing them to increasingly loud noise.
Pachel said those treatments or combinations of them work for many dogs, but the tranquilizers can take days to wear off, and anti-anxiety pills can cause appetite problems, upset stomach and, rarely, abnormal heartbeats if the dose isn’t right.
Sileo works by blocking norepinephrine, a brain chemical similar to adrenaline that pumps up anxiety. It comes in prefilled plastic syringes with a dial for setting a precise dose according to the dog’s weight.
The needleless syringe is placed between the dog’s gum and lip. A little push ejects a small amount of gel that’s absorbed by the tissue lining the dog’s cheek, which limits how much circulates in the dog’s body at once while enabling the medicine to start working within 30 to 60 minutes. It works for two to three hours, said McFarland.
Each syringe costs $30 and holds enough medicine for about two doses for an 80- to 100-pound dog or four doses for a 40-pound dog. Side effects are rare and minor.
