Taylor Mills had 14 points and 12 rebounds as La Center rode its defense to a win.
The Wildcats held Seton Catholic to 6 for 34 from the field.
Andrea Griffee had eight assists. Bethany Whitten added five steals and four assists.
La Center’s victory sets up a Friday showdown in Kalama. The Wildcats (18-1, 11-0) would clinch the 1A Trico League title outright with a win.
Kailey Beckwith scored nine points to lead Seton Catholic (8-11, 4-7).
LA CENTER 60, SETON CATHOLIC 19
SETON CATHOLIC — Megan McDaid-O’Neill 0, Elena Carrion 0, Kailey Beckwith 9, Elizabeth Sheldon 4, Amy Fraizer 2, Emily Martin 1, Nami Nsubuga 1, Katherine Zdunich 0, Annalei Santos 2. Totals 6 (3) 4-9 19.
LA CENTER — Ashley Denney 5, Whitley Seter 0, Bethany Whitten 4, Lauryn Powers 4, Shelby Vermeulen 8, Laynie Erickson 10, Taylor Mills 14, Andrea Griffee 2, Taylor Stephens 11, Alyssa McKnight 2. Totals 23 (3) 11-19 60.